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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16156 | MT 63-78 | Apoptosis , AMPK , mTOR | |
MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM). MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects. MT 63–78 also causes cel... | |||
T7519 | RS-127445 hydrochloride | RS 127445,MT 500 | 5-HT Receptor |
RS-127445 hydrochloride (MT 500) is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist(pKi : 9.5). | |||
T39461 | MT1 | ||
MT1, a bivalent chemical probe targeting BET bromodomains, demonstrates an IC50 value of 0.789 nM for BRD4(1). | |||
T11465 | Lenacapavir | GS-6207 | Others , HIV Protease |
Lenacapavir (GS-6207) is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells. | |||
T61569 | Mt KARI-IN-1 | ||
Mt KARI-IN-1 is a lead compound that demonstrates strong inhibitory activity towards Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 3.06 μM [1]. | |||
T10305 | Amiselimod hydrochloride | MT-1303 hydrochloride | S1P Receptor , LPL Receptor |
Amiselimod hydrochloride (MT-1303 hydrochloride) is a sphingosine 1-phosphate receptor-1 (S1P1) modulator. | |||
T16157 | MT-802 | BTK , PROTACs | |
MT-802 is an effective BTK degrader based on PROTAC technology (DC50: 1 nM). MT-802 has the potential to treat C481S mutant chronic lymphocytic leukemia (CLL). | |||
TQ0174 | Mavorixafor | AMD-070 | CXCR |
Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC... | |||
T67833 | HIV-1 inhibitor-54 | HIV Protease | |
HIV-1 inhibitor-54 is a potent HIV-1 inhibitor showing anti-HIV activity (EC50 : 32 nM) against WT HIV-1 (strain IIIB) x in MT-4 cells.HIV-1 inhibitor-54 can be used to study viral infections. | |||
T17319 | 1,2-Bis(2-iodoethoxy)ethane | Others , PROTAC Linker | |
1,2-Bis(2-iodoethoxy)ethane is a PEG-based PROTAC linker. 1,2-Bis(2-iodoethoxy)ethane can be used in the synthesis of MT802 and SJF620. MT-802 and SJF620 are potent PROTAC BTK degraders with DC50s of 1 nM and 7.9 nM, res... | |||
T4S1521 | 1,4-Dicaffeoylquinic acid | HIV Protease | |
1,4-Dicaffeoylquinic acid has antioxidant activity.1,4-Dicaffeoylquinic acid is a potent and highly selective class of HIV-1 integrase inhibitors, inhibitsHIV-1 replication in MT-2 cell culture at non-toxic concentration... | |||
T25310 | Dersimelagon | MT-7117 | Melanocortin Receptor |
Dersimelagon (MT-7117) is an orally active, selective agonist for the melanocortin 1 receptor (MC1R), demonstrating EC50 values of 8.16 nM (h), 3.91 nM (cm), 1.14 nM (m), and 0.251 nM (r) across species such as human, cy... | |||
T7208 | AMD 3465 hexahydrobromide | GENZ-644494 (hexahydrobromide) | HIV Protease , CXCR |
AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity. | |||
T60490 | Melatonin receptor agonist 1 | ||
Melatonin receptor agonist 1 (compound 20c) is a potent agonist of melatonin receptor (MT) with Ki values of 108 nM for MT2 and 1140 nM for MT 1 [1]. | |||
T10296 | Mavorixafor trihydrochloride | AMD-070 trihydrochloride | HIV Protease |
Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs (I... | |||
T82438 | Etedesiran | ||
Etedesiran acts as an inhibitor of Myotonin-protein kinase (MT-PK, MDPK, or DMPK) [1]. | |||
T11693L | IT1t dihydrochloride | CXCR | |
IT1t dihydrochloride inhibits CXCL12/CXCR4 interaction with IC50 of 2.1 nM. IT1t dihydrochloride is an antagonist of CXCR4. | |||
T79029 | IpOHA | ||
IpOHA is a potent inhibitor of plant KARI and functions as an antimycobacterial agent, demonstrating a K_i value of 97.7 nM against Mycobacterium tuberculosis (Mt) [1]. | |||
T61570 | Mt KARI-IN-2 | ||
Mt KARI-IN-2 (compound 5b) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 2.02 μM. This compound also exhibits inhibitory activity against Mtb H37... | |||
T62782 | HIV-1 inhibitor-34 | ||
HIV-1 inhibitor-34 (compound 5q) is a potent, selective HIV-1 inhibitor that acts on HIV-1 (EC50: 6.4 nM), MT-4 cells (CC50: 16 μM). HIV-1 inhibitor-34 can be used in AIDS research. |